- October 19, 2022
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- Lakewood Ranch High had its Thursday night home game against Lemon Bay High canceled because of lightning.
- The Out-of-Door Academy defeated Berean Christian 28-0 on the road on Saturday. ODA had 256 rushing yards, including a 77-yard touchdown by senior running back Griffin DeRusso.
- Braden River High had an off week.
- Parrish Community High defeated Poinciana High 39-15 at home.
- Cardinal Mooney High defeated Booker High 10-9 at home.
- Sarasota High defeated Bayshore High 56-8 at home. Junior Jaden Judge and sophomore Takurian Smith had two rushing touchdowns each for the Sailors.
- Riverview High lost 48-0 on the road to (Sanford) Seminole High.